The Immunohistochemical Characterization of Devil Facial Tumor Disease (DFTD) in the Tasmanian Devil (Sarcophilus harrisii)
نویسندگان
چکیده
منابع مشابه
The pathology of devil facial tumor disease (DFTD) in Tasmanian Devils (Sarcophilus harrisii).
A disfiguring and debilitating neoplastic condition known as devil facial tumor disease (DFTD) has been discovered in wild Tasmanian Devils (Sarcophilus harrisii) across 51% of its natural range, with population declines of up to 80% in some areas (C. Hawkins, personal communication). Between 2001 and 2004, 91 cases were examined. The tumors presented as large, solid, soft tissue masses usually...
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Tasmanian devil joeys, like other marsupials, are born at a very early stage of development, prior to the development of their adaptive immune system, yet survive in a pathogen-laden pouch and burrow. Antimicrobial peptides, called cathelicidins, which provide innate immune protection during early life, are expressed in the pouch lining, skin and milk of devil dams. These peptides are active ag...
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The Tasmanian devil (Sarcophilus harrisii) is a carnivorous marsupial found only in the wild in Tasmania, Australia. Tasmanian devils are classified as endangered and are currently threatened by devil facial tumour disease, a lethal transmissible cancer that has decimated the wild population in Tasmania. To prevent extinction of Tasmanian devils, conservation management was implemented in 2003 ...
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The global extirpation of the world’s apex predator fauna is consistently highlighting their important functional role in preserving biodiversity and maintaining ecosystem resilience. Apex predator declines and extinctions are promoting more invasive and homogenised ecosystem states, linked with secondary species extinctions, changes to community composition, and redefined carnivore guilds. In ...
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ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 2006
ISSN: 0300-9858,1544-2217
DOI: 10.1354/vp.43-6-896